Background: The musculoskeletal discomfort mainly due to two reasons, i.e the harmful working condition and posture demands of the work place leading to musculoskeletal problems. The risk of developing musculoskeletal problems is mainly due to the inconvenient work posture [4]. The work related musculoskeletal disorder primarily caused by repetitive movements, poor posture, continuous static work, frequent bending [4]. Because poor posture the body is distress resulting decreased efficiency of performance work because they work in sitting posture for long periods with shoulders flexed and abducted, head and trunk flexed forward [2]. when work related musculoskeletal disorder developed in the tailors, then they experienced the pain, stiffness and loss of rom and inability to work ADL [5]. Majority of the tailors felt pain in neck, shoulders, thighs and legs as they are exposed to high level of repetitive task and work pressure.[5]Musculoskeletal complaints regarding neck region are extensively present in tailor [2]. as this profession involves highly monotonous, repetitive work in sitting position with bent neck [2]. Kinesiology tape- it is improved version of elastic tape that acts to dynamically assist your muscle function. K- taping application affects muscular and myofascial function which help in reducing the tension over the muscles. [13] application of tape lifts the skin and directly reduces pressure on subcutaneous nociceptors [13], also the tape alter the afferent sensory signals, which would lead to the facilitation of pain inhibitory mechanisms, causing a reduction in pain.[11] Objective: To Find Effectiveness of Taping On Neck Pain And Neck Disability Index In Tailors – An Experimental Study. Methodology: Ethical clearance was obtained from institution informed consent was taken from participants. Participants were screened according to inclusion and exclusion criteria. Purpose of study and procedure was explained to participants. The subjects were assessed for neck pain by using NPRS and NDI. Kinesio tape was applied to subjects in sitting position. Subjects were reassessed after 48 hours for neck pain by using NPRS and NDI. Result: Total 40 tailors were assessed for neck pain by using NPRS and NDI. Statistical analysis is done by using paired t test. Conclusion: The study concludes that the application of kinesio tape shows significant effect on reducing neck pain and disability in tailors.